About Tesamorelin
What is Tesamorelin?
Tesamorelin (CAS 218949-48-5) is a stabilised analogue of growth-hormone-releasing hormone (GHRH). It acts at the GHRH receptor, upstream of ghrelin-receptor secretagogues such as ipamorelin. A trans-3-hexenoyl group on the N-terminus improves stability versus native GHRH.
Werhner Lab supplies tesamorelin as lyophilised powder in 10 mg vials.
CAS: 218949-48-5. Molecular weight: ~5135.9 g/mol. Target: GHRH-R.
How Tesamorelin is studied in the literature
The literature treats tesamorelin as a GHRH-receptor tool for GH-axis and metabolic models. Background only; not a claim about individual effects.
GHRH-receptor and GH-cascade research
Used to study receptor activation, GH release, and downstream IGF-axis biochemistry in controlled models.
Metabolic and body-composition models
Also appears in work on visceral-adipose and metabolic signalling that starts from GHRH-style stimulation rather than GHS-R.
Within the class — how Tesamorelin differs
Tesamorelin is not a GHRP. Ipamorelin pushes the ghrelin receptor. Tesamorelin mimics hypothalamic GHRH. Labs pick it when the question is the GHRH receptor itself, or an upstream trigger of the GH axis.
Research areas
- GHRH-receptor pharmacology
- GH / IGF-axis cascade models
- Comparison of GHRH analogues versus GHS-R secretagogues
- Peptide-stability work on N-terminally modified GHRH
Specifications
| CAS | 218949-48-5 |
| Molecular weight | ~5135.9 g/mol |
| Receptor profile | GHRH-R agonist |
| Purity | ≥ 97.5% (batch CoA) |
| Form | Lyophilised powder, sealed vial |
| Size | 10 mg |
Storage
Powder: −20°C long term; 2–8°C short term.
Reconstituted: 2–8°C; do not freeze unless the protocol requires it.
Quality
Batch CoA on request. Batch example: TM10-6127.
Important notice — Research Use Only
Tesamorelin is supplied by Werhner Lab for laboratory research only. Not a medicine or supplement. Not for human consumption.