About Ipamorelin
What is Ipamorelin?
Ipamorelin (CAS 170851-70-4) is a synthetic pentapeptide growth-hormone secretagogue. It binds the ghrelin receptor (GHS-R / GHRP receptor) and is used when a lab needs a selective GH-axis stimulus rather than an older, less selective GHRP.
Werhner Lab supplies ipamorelin as lyophilised powder in 10 mg vials.
CAS: 170851-70-4. Molecular weight: ~711.9 g/mol. Target: GHS-R.
How Ipamorelin is studied in the literature
Papers describe ipamorelin as a selective ghrelin-mimetic used in pituitary and GH-release models. The notes below are research background only.
GH-axis and pituitary signalling
Used to study growth-hormone release cascades with less off-target movement of cortisol and ACTH than GHRP-2 or GHRP-6 in many published comparisons.
Receptor selectivity models
Chosen when the design needs GHS-R activation without a strong appetite or prolactin signal.
Within the GH-secretagogue class — how Ipamorelin differs
| Feature | GHRP-2 / GHRP-6 | Ipamorelin | Tesamorelin |
|---|---|---|---|
| Main target | GHS-R (less selective) | GHS-R (more selective) | GHRH receptor |
| Length | Short peptide | 5 amino acids | GHRH analogue (long) |
| Typical research angle | Broad GH pulse + more side signals | Cleaner GHS-R model | Upstream hypothalamic-style signal |
Ipamorelin does not replace a GHRH analogue. It works at a different receptor.
Research areas
- Ghrelin-receptor binding and signalling
- Pituitary GH-release models
- Selectivity versus first-generation GHRPs
- Combination designs with GHRH analogues (separate compounds)
Specifications
| CAS | 170851-70-4 |
| Molecular weight | ~711.9 g/mol |
| Receptor profile | GHS-R agonist (secretagogue) |
| Purity | ≥ 97.5% (batch CoA) |
| Form | Lyophilised powder, sealed vial |
| Size | 10 mg |
Storage
Powder: −20°C long term; 2–8°C short term.
Reconstituted: 2–8°C; follow lab SOP. Avoid repeat freeze–thaw.
Quality
Batch CoA on request. Batch example: IP10-9014.
Important notice — Research Use Only
Ipamorelin is supplied by Werhner Lab for laboratory research only. Literature notes are background, not medical claims. Not a medicine or supplement. Not for human consumption.